Both Ajax and Atalanta seek crucial points as they clash in Amsterdam following contrasting European openers.
Omonia Nicosia and Benfica look to maintain their flawless Europa League starts when they meet in Round 3 on Thursday night.
In-form Olympiacos target a third consecutive Europa League victory as undefeated Sparta Prague visit the Georgios Karaiskakis Stadium.
Two flawless records collide as European heavyweights Paris Saint-Germain and Barcelona square off in Round 3 of the Champions League.
Porto look to bounce back from European setbacks as an injury-hit PSV Eindhoven arrive at Estadio do Dragao.
Form, team news, key player matchups, and tactical outlook ahead of Saturday's Premier League showdown.
Germany's top two scoring sides square off in Munich as Bayern look to bounce back from back-to-back draws against a booming Leipzig attack.
Two European heavyweights collide in Copenhagen as FC Copenhagen seek home advantage against Portuguese contenders Braga.
High-flying Benfica look to maintain their perfect European record at home as Celtic search for a vital bounce-back performance in Lisbon.
In-form Sparta Prague aim to keep their perfect streak going when they welcome Norwegian side Lillestroem to epet ARENA.
Unai Emery seeks to turn Villa Park into a fortress once more as Aston Villa face Fenerbahce in the UEFA Champions League, with Leon Goretzka making his squad return.
Manuel Pellegrini's high-flying Betis seek another European victory as Francesco Farioli's Benfica target their first Champions League points of the campaign at Estadio Benito Villamarin.